Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 8;8:14674. doi: 10.1038/ncomms14674

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

MAX restoration in MAX-mutant (homozygous deletion) GIST48 cell line restores p16 expression and inhibits CDK4/6-dependent phospho-RB1^Ser795; GAPDH serves as loading control and the bar graph normalizations of GIST48 versus GIST48MAX are with the higher value set to 100% (a). Restoration of MAX expression inhibits GIST48 growth, as assessed by cell counts at 24 h (P=0.0488) and 72 h (P=0.0029) (b), and inhibits GIST proliferation index, as assessed by BrdU incorporation at 24 h (P=0.0130) (Student's t-test) (c). Tests were performed in triplicate. The error bars show s.d. (b) and s.e.m. (c).