Figure 3. Effects of BACE1 deletion on body weight.
(a) Both male and female Bace1−/− mice showed significantly reduced body weights relative to wildtype controls. (b) Both male and female Bace1−/− rats had similar body weights relative to Bace1+/+ controls. Mice and rats were ~20 weeks old when weights were taken. ***p < 0.0001. Values are mean ± SEM, numbers represent sample size (number of animals, n).