Table 1. Summary of the endocrine-disrupting signatures of each tested analgesic ex vivo.

Cell type	Hormone	Paracetamol	Ibuprofen	Aspirin	Indomethacin
Leydig cell	Testosterone	⇔	1
	INSL3			⇔	⇔
Sertoli cell	AMH	⇔			⇔
Unknown	PGD2	⇔	⇔	⇔	⇔
	PGE2		or 2

Data for paracetamol, aspirin and indomethacin come from²⁶.

¹After 24, 48 and 72 h of exposure.

² In the 8–9.9 GW and 8–12 GW testes at 10⁻⁵ and 10⁻⁴M; in the 10–12 GW testes at 10⁻⁷ and 10⁻⁶M.