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. 2017 Mar 9;8:51. doi: 10.1186/s13287-017-0502-9

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — PTH induces hMSC differentiation into osteoprogenitor cells. Immunohistochemistry was performed on tissue samples harvested 8 weeks after surgery. The sections were stained with antibodies against the well-established osteogenic markers osteocalcin (Oc) and bone sialoprotein (BSP), in addition to DAPI staining. Yellow arrows indicate bone defect margins; orange arrows indicate co-staining of DiI and bone markers. MSCs mesenchymal stem cells, PTH parathyroid hormone