Table 1.
Drug | hESC-CMs | hiPSC-CMs | ||
---|---|---|---|---|
CI (μmol•L-1) | IC50/EC50 (μmol•L-1) | CI (μmol•L-1) | IC50/EC50 (μmol•L-1) | |
E-4031 | 0.01↑ | 0.02 | 0.1↓ | 0.04 |
Isoprenaline | 0.1↓ | 0.04 | 1↓ | 0.03 |
Quinidine | 100↓ | 2.18 | 100↓ | 13.97 |
Haloperidol | NO | 0.14 | 10↓ | 5.17 |
CI cell index, hESC-CMs human embryonic stem cells-derived cardiomyocytes, hiPSC-CMs human induced pluripotent stem cells-derived cardiomyocytes