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. 2017 Mar 9;36:28. doi: 10.1186/s40880-017-0193-8

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Models and transitions of tumor cell metastasis. a Migration of whole groups of cancer cells; b migration of individual cancer cell. EMT epithelial-mesenchymal transition, MAT mesenchymal-amoeboid transition, AMT amoeboid-mesenchymal transition, ZEB1/2 zinc finger E-box-binding homeobox 1 and 2