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NOS activity measured in homogenates of intact aortas of control (CON, n = 3) and hypercholesterolemic (HC, n = 6) rabbits. Citrulline formation from arginine was determined in the presence (total NOS) and absence (inducible NOS, iNOS) of free Ca2+; constitutive NOS (cNOS) activity was calculated by subtracting iNOS from total activity for each individual rabbit. Data are represented as mean ± SEM; n.s., not significant.
