Fig. 1.

Cutaneous and systemic IMQ responses. a IMQ dermatitis in B6, BALB/c, and MOLF mice. b Weight loss following IMQ treatment (*P < 0.05, IMQ versus sex-matched control). c Epidermal thickness (*P < 0.05, IMQ versus sex-matched control; measured using microscopy). d Spleen weight (*P < 0.05, IMQ versus sex-matched control). e–g CTL-treated samples. h–j IMQ-treated samples. In e–j, groups without the same letter differ significantly (P < 0.05, Tukey honest significant difference). In b–j, three to five mice were evaluated for each strain, sex, and treatment (error bars represent standard error of the mean). F female, M male