Table 3.
Stratified analysis of rs35301225 genotype in clinical characteristic of gastric cancer patients
Feather | Genotype | CC vs. AA P value* |
CC vs. A carrier P value* |
|||
---|---|---|---|---|---|---|
CC | CA | AA | A carrier | |||
Age (years) | ||||||
≤50 | 99 | 81 | 196 | 277 | 0.258 | 0.4399 |
>50 | 90 | 74 | 145 | 219 | ||
Gender | ||||||
Male | 80 | 69 | 169 | 238 | 0.11 | 0.1990 |
Female | 109 | 86 | 172 | 258 | ||
Differentiation grade | ||||||
Well | 102 | 75 | 72 | 147 | <0.0001 | <0.0001 |
Moderate | 48 | 69 | 74 | 143 | ||
Poor | 39 | 11 | 195 | 206 | ||
Tumor size (cm) | ||||||
≤5 | 157 | 144 | 177 | 321 | <0.0001 | <0.0001 |
>5 | 32 | 11 | 164 | 175 | ||
Metastasis | ||||||
Yes | 147 | 134 | 131 | 265 | <0.0001 | |
No | 42 | 21 | 210 | 231 | <0.0001 |
* Two-sided Chi square test for either genotype distributions or allele frequencies between cases and controls