Table 1.
Basic characteristics of the study subjects
| GC cases | Controls | Severe IM/dysplasia | |
|---|---|---|---|
| n | 501 | 489 | 283 |
| Age, n (%) | |||
| <58 | 246 (49.1) | 233 (47.6) | 133 (47.0) |
| ≥58 | 255 (50.9) | 256 (52.4) | 150 (53.0) |
| P a | 0.647 | 0.861 | |
| Sex, n (%) | |||
| Male | 365 (72.9) | 352 (72.0) | 153 (54.1) |
| Female | 136 (27.1) | 137 (28.0) | 130 (45.9) |
| P a | 0.759 | <0.001 | |
| Smoking, n (%) | |||
| Yes | 199 (46.9) | 196 (40.1) | 112 (39.6) |
| No | 225 (53.1) | 293 (59.9) | 171 (60.4) |
| P a | 0.037 | 0.890 | |
| Alcohol drinking, n (%) | |||
| Yes | 186 (44.3) | 119 (24.3) | 65 (23.0) |
| No | 234 (55.7) | 370 (75.7) | 217 (77.0) |
| P a | <0.001 | 0.687 | |
| H. pylori infection, n (%) | |||
| Positive | 431 (88.0) | 280 (57.4) | 217 (78.3) |
| Negative | 59 (12.0) | 208 (42.6) | 60 (21.7) |
| P a | <0.001 | <0.001 | |
| Type of H. pylori infection, n (%) | |||
| CagA+ | 322 (65.7) | 158 (32.4) | 115 (41.5) |
| CagA− | 168 (34.3) | 330 (67.6) | 162 (58.5) |
| P a | <0.001 | 0.011 | |
| Type of H. pylori infection, n (%) | |||
| VacA+ | 228 (46.5) | 137 (28.1) | 85 (30.7) |
| VacA− | 262 (53.5) | 351 (71.9) | 192 (69.3) |
| P a | <0.001 | 0.444 | |
| Type of H. pylori infection, n (%) | |||
| Type I | 329 (67.1) | 163 (33.4) | 133 (48.0) |
| Type II | 102 (20.8) | 117 (24.0) | 84 (30.3) |
| Not infected | 59 (12.1) | 208 (42.6) | 60 (21.7) |
| P a | <0.001 | <0.001 | |
| Cancer site, n (%) | |||
| Cardia | 74 (16.2) | ||
| Noncardia | 384 (83.8) | ||
| Stage, n (%) | |||
| Stage I/II | 98 (25.8) | ||
| Stage III/IV | 282 (74.2) | ||
a
P values for chi‐square test.