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. 2016 Nov 7;21(4):685–696. doi: 10.1111/jcmm.13012

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© 2016 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Effect of BDNF on oxidative stress and cardiac function of Dox‐treated rats by echocardiography. (A and D) Superoxide dismutase (SOD) activity, (B and E) malondialdehyde (MDA) level and (C and F) reduced glutathione (GSH) content in left and right rat ventricles. (G) Representative images of cardiac function. (H) Ejection fraction (EF). (I) Fractional shortening (FS). (J) LV end systolic volume (LVESV). (K) LV end diastolic volume (LVEDV). *P < 0.05 versus sham, #P < 0.05 versus Dox, n = 5 each group.