Skip to main content
. 2017 Jan 30;6(3):547–554. doi: 10.1002/cam4.1004

Table 3.

Comparison of clinicopathological features between BRCA1 rs80350973 mutation carriers and noncarriers

Characteristic Noncarriers (n = 116) rs80350973 carriers (n = 9) P‐value
Age at diagnosis (years)
>35 102 7 0.382
≤35 14 2
Histology of primary tumor
Ductal 100 7 0.598
Lobular 8 0
Others 7 1
Primary tumor size
T1 44 1 0.343
T2 45 6
T3 9 1
T4 7 1
Axillary node involvement
N0 51 7 0.253
N1 23 0
N2 20 1
N3 19 1
TNM Stage
I 24 1 0.426
II 43 6
III 35 2
IV 7 0
Family history
Yes 9 2 0.140
No 107 7
Visceral metastases at relapsea
Negative 61 6 0.415
Positive 55 3
Ki‐67 index
Median 0.48 0.75 0.004
Range 0.00~0.98 0.50~0.90
a

Patient with one or more metastatic sites including lung, liver, or brain at time of relapse was defined as visceral metastasis positive, otherwise, the patients were defined as negative.