Figure 4.

Mechanical antiallodynic effects of repeated daily intrathecal injections of morroniside (100 μg) in a rat model of neuropathic pain. Peripheral neuropathy was induced by tight ligation of L5/L6 spinal nerves and the paw withdrawal thresholds were measured using an electronic von Frey filaments 1 h after each drug administration. Data are presented as means ± SEM; n = 6 for each group. *P < 0.05, significantly different from saline control group; repeated measures two‐way ANOVA followed by post hoc Student–Newman–Keuls test.