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Neurokinin receptor 1 (NK1r)‐IR. In control and OB/WRS rats, the NK1r labelling is mainly located along the neuronal plasma membrane (A and C) while in the WRS rats (B) the majority of the neurons are labelled also in the cytoplasm. MP: myenteric plexus. Bar: A–C = 25 μm. (D) The quantification of the myenteric neurons shows that in the WRS animals, there is a significant decrease in their number respect to controls and OB/WRS rats (*P < 0.02).
