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Effects of RPS3 gene silencing on HDM‐induced AHR. AHR in response to increasing concentrations of aerosolized methacholine was measured 24 h after the last challenge with (pretreatment) 5 nmol control or RPS3 siRNA. AHR is expressed as percentage change compared with the baseline level of (A) lung resistance (Rl; n = 6) and (B) dynamic compliance (Cdyn; n = 6). Values are shown as means ± SEM. *Significant difference from control siRNA, P < 0.05.
