Table 1. Comparison of lethality, developmental delay, and body size on knocking out dSTIM or reducing dOrai function.
Genotype | Percentage Lethality | Developmental Delay | Small Body Size |
---|---|---|---|
STIMko | 100 | ++ | ++ |
orai3 | 80 | ++ | ++ |
ElavC155 > cas9;STIMdual | 45 | + | — |
nSyb > cas9;STIMdual | 40 | + | — |
TH > cas9;STIMdual | 98 | ++ | ++ |
THA > cas9;STIMdual | 50 | + | + |
, strength of phenotype; —, no phenotype; TH, tyrosine hydrolase.