Table 1. Functional categories of differentially expressed genes.
| Functional Categorya | Numbers of Annotated Genes Differentially Expressed | ||
|---|---|---|---|
| Upregulated (Hypergeometric probability) | Downregulated (Hypergeometric probability) | Total | |
| Conserved Hypotheticals (1042)b | 40 (0.061759406)c | 67 (8.16275E-07) | 107 |
| Cell Wall and Cell Processes (772) | 19 (0.001995823) | 91 (0.010574298) | 110 |
| Intermediary Metabolism & Respiration (936) | 32 (0.03347788) | 79 (0.008638868 | 111 |
| Virulence, Detoxification, Adaptation (239) | 5 (0.035212069) | 21 (0.074186339) | 26 |
| Lipid Metabolism (272) | 10 (0.120666963) | 30 (0.068644912) | 40 |
| PE/PPE (168) | 14 (0.005487782) | 10 (0.020306077) | 24 |
| Regulatory Proteins (198) | 10 (0.108673767) | 18 (0.090307358) | 28 |
| Information Pathways (242) | 2 (0.001542606) | 51 (6.06728E-08) | 53 |
| Insertion Sequences and Phages (147) | 6 (0.166936362) | 8 (0.017835861) | 14 |
| Unknown (15) | 1 (0.34490959) | 1 (0.342707614) | 2 |
| Total | 139 | 376 | 515 |
a Functional Categories as designated on the Tuberculist website (http://tuberculist.epfl.ch)
b Numbers in parentheses indicate total number of genes in the category in the M. tb H37Rv genome.
c Number in parentheses indicate hypergeometric probability p value and bold values indicate statistical significance at p<0.05