Table 1.

Patient characteristics.

Patient	Age	Sex	Preoperative PCA group	Postoperative PCA group	Primary tumor location	Primary resected	Stage	Active disease (at preoperative blood draw)	Procedure	Largest tumor foci of specimen	Recurrence	Survival
1	52	M	A	A	Right arm	Yes (2 mo prior) T3a—2.8 mm 0/3 SLNB—right axilla	IV	Left axilla	Left ALND 9/55 nodes positive	3 cm	Yes 5 mo	Dead 35 mo
2	81	M	B	A	Left shoulder	Yes (1 y prior) T4a—4.6 mm deep 2/2 SLNB—left axilla	IIIc	Left axilla	Left ALND 5/47 nodes positive	1.6 cm	Yes 5 mo	Dead 11 mo
3	71	F	B	A	Unknown primary	NA	IIIc	Left axilla	Left ALND 5/31 nodes positive	9.9 cm	Yes 5 mo	Dead 22 mo
4	71	F	B	B	Right heel	Yes (5 y prior) T2b—10 mm deep 0/4 SLNB—right inguinal	IV	Metastatic cutaneous lesion of left groin	WLE of metastatic cutaneous lesion	3.4 cm	Yes 5 mo	Dead 24 mo
5	30	M	A	A	Unknown primary	NA	IV	Abdominal wall	Wide excision of abdominal wall	4.7 cm	No (18 mo)	Alive
6	56	M	A	A	Right calf	Yes (3 y prior) T4b—4.6 mm 0/2 SLNB—right axilla	IV	Malignant enterocolonic fistula Liver Lung	Small bowel resection Left hemicolectomy Hepatic wedge resection (Pulmonary metastasis not resected)	5.5 cm	Remaining distant metastatic disease at time of resection	Dead 30 mo

Abbreviations: ALND, axillary lymph node dissection; PCA, principal component analysis; SLNB, sentinel lymph node biopsy, expressed as ratio of number of lymph nodes containing microscopic disease relative to the total number of lymph nodes biopsied; WLE, wide local excision; NA, Not applicable (unknown primary).

Six patients undergoing surgical resection of melanoma lesions were classified according to pathologic stage and grouping on PCA before and after surgical resection.