Fig. 1.

A) MDSQ mean score of the scales mood and agitation for panic patients, phobic individuals and controls subjects. Bar plots show the participants' subjective mood state in response to the three threat conditions unpredictable, predictable and no threat. B) Subjective arousal in response to the predictable or unpredictable threat. Higher values (SAM rating scale 0–9) indicate stronger agitation (arousal). Error bars depict standard error of the mean. C) Correlation of panic and phobic patients' vmPFC neural activity within 270–470 ms under unpredictable threat conditions with the subjective arousal rating of the unpredictable threat stimulus.