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. 2017 Mar 6;11:659–668. doi: 10.2147/DDDT.S127328

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© 2017 Su et al. This work is published and licensed by Dove Medical Press Limited

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Confocal laser scanning microscopy images of A875 cells after 2 h of incubation with C6-loaded CA-PLGA-TPGS NPs. C6-loaded NPs were green, and the cells were stained by PI (red). The cellular uptake was observed by overlaying images obtained by FITC channel (green) and PI channel (red). Magnification ×0.5 k.

Abbreviations: C6, coumarin-6; CA, cholic acid; PLGA, poly(lactide-co-glycolide); TPGS, D-α-tocopheryl polyethylene glycol 1000 succinate; NPs, nanoparticles; PI, propidium iodide; FITC, fluorescein isothiocyanate.