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Characterizations of PTX-loaded NPs (n=3)
| Polymer | Size (nm) | PDI | ZP (mV) | LC (%) | EE (%) |
|---|---|---|---|---|---|
| PLGA | 179.5±7.5 | 0.166 | −28.7±3.4 | 7.98 | 80.21 |
| PLGA-TPGS | 160.4±6.7 | 0.152 | −16.8±2.5 | 8.22 | 88.43 |
| CA-PLGA-TPGS | 125.6±5.3 | 0.131 | −11.5±1.8 | 10.46 | 98.52 |
Abbreviations: PTX, paclitaxel; NPs, nanoparticles; PDI, polydispersity index; ZP, zeta potential; LC, loading content; EE, encapsulation efficiency; PLGA, poly(lactide-co-glycolide); TPGS, D-α-tocopheryl polyethylene glycol 1000 succinate; CA, cholic acid.
