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. 2017 Mar 6;11:553–562. doi: 10.2147/DDDT.S113289

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© 2017 da Silva et al. This work is published and licensed by Dove Medical Press Limited

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Exercise tolerance was improved with LASSBio-294 treatment. Measurements performed 4 weeks after surgery. SHR-Sham treated with DMSO and SHR-MI treated with DMSO or LASSBio-294 orally, 10 and 20 mg.kg⁻¹. Data are expressed as mean ± SEM.

Notes: *P<0.05 compared to SHR-Sham; ^&P<0.05 compared to SHR-MI; ^&&P<0.01 compared to SHR-MI, n=6.

Abbreviations: DMSO, dimethyl sulfoxide; MI, myocardial infarction; SHR, spontaneously hypertensive rats; LASSBio-294, 3,4-methylenedioxybenzoyl-2-thieny lhy-drazone; po, by mouth.