Table 4.
Estimation of the stiffness of engineered extracellular matrix in pulmonary conduits in an ovine model. Scaffold volume fraction decreases with implant time as fibers are degradable and absorbed by the host body. The stiffness of the produced ECM does not change appreciable from the values observed post-implantation during these first few days after implant.
| n | scaffold volume fraction ϕf |
engineered ECM stiffness μm (kPa) |
|
|---|---|---|---|
| pre-incubation | Eckert et al. (2011) | 0.0702 ± 0.0102 | |
| t = 0 day | 4 | 0.0460 ± 0.0041 | 5.173 ± 0.393 |
| t = 1 day | 5 | 0.0397 ± 0.0064 | 8.1318 ± 1.370 |
| t = 7 day | 4 | 0.0253 ± 0.0042 | 18.138 ± 4.144 |