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. Author manuscript; available in PMC: 2018 Mar 10.
Published in final edited form as: ACS Infect Dis. 2017 Feb 8;3(3):225–236. doi: 10.1021/acsinfecdis.6b00202

Scheme 6. 1 cyclohexyl linker replacement synthesis.

Scheme 6

Reagents and conditions: (a) Boc2O, CH2Cl2, 0 °C→rt, o.n.; (b) 20, toluene, µW, 150 °C, 6 hrs; (c) TFA, CH2Cl2, rt, o.n.