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Single-cell ATAC-seq. (a) The workflow of scATAC-seq to measure single cell accessibility on a C1 microfluidic device (Fluidigm). (b) Aggregated single-cell accessibility profiles are similar to profiles of DNase-seq and ATAC-seq in GM12878 cells. Reprinted with permission from Buenrostro et al., Nature 523(7561), 486–490 (2015). Copyright 2015 Macmillan Publishers Ltd.
