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A microfluidic device for DNA and RNA analysis from the same cell. Schematics of the process flow. (a) A single cell is trapped in a small chamber. (b) The captured single cell is lysed by the membrane-selective lysis buffer. (c) RNA is separated from the intact nucleus and reverse transcribed to cDNA. (d) cDNA and gDNA are subjected to whole pool amplification. Reprinted with permission from Han et al., Sci. Rep. 4, 6485 (2014). Copyright 2014 Macmillan Publishers Ltd.
