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. 2017 Mar 10;12(1):27. doi: 10.1007/s11657-017-0321-8

Table 2.

Changes in outcome measures between baseline and the 3-month follow-up

Outcome measures BIS initiation at week 2 (n = 45) BIS initiation at week 12 (n = 45) p value
de Morton Mobility Index
 Baseline
 3-month follow-up
 Change in scores
39.0 ± 8.5
61.0 ± 17.9
22.0 ± 14.1
37.8 ± 9.8
62.7 ± 19.0
25.0 ± 15.7
0.522
0.327
0.345
Barthel Index
 Baseline
 3-month follow-up
 Change in scores
57.6 ± 15.1
86.4 ± 13.9
28.8 ± 15.1
59.9 ± 16.8
86.6 ± 14.9
26.7 ± 13.1
0.491
0.668
0.459
EuroQol visual analog scale
 Baseline
 3-month follow-up
 Change in scores
61.0 ± 15.3
75.5 ± 15.9
14.5 ± 16.0
63.1 ± 15.9
78.8 ± 13.9
15.7 ± 16.5
0.527
0.406
0.732
Visual analog scale
 Baseline
 3-month follow-up
 Change in scores
2.7 ± 2.3
1.1 ± 1.9
−1.8 ± 2.6
2.7 ± 2.5
1.1 ± 1.3
−1.6 ± 2.3
0.930
0.977
0.931
Outcome measures BIS initiation at week 2 (n = 44) BIS initiation at week 12 (n = 42) p value
Two-minute walking test (m)
 Baseline
 3-month follow-up
 Change in scores
17.4 ± 18.2
40.5 ± 20.9
23.1 ± 23.0
15.9 ± 8.7
38.8 ± 25.3
22.9 ± 19.8
0.621
0.885
0.971
Timed get-up-and-go test (s)
 Baseline
 3-month follow-up
 Change in scores
71.0 ± 40.3
28.3 ± 16.8
−42.7 ± 33.4
66.1 ± 46.1
32.5 ± 22.1
−33.5 ± 42.9
0.600
0.166
0.272

Data presented as mean ± standard deviation; p value <0.05 indicates statistical significance

BIS bisphosphonate