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. 2004 Nov 16;32(20):6001–6014. doi: 10.1093/nar/gkh923

Figure 2.

Figure 2

Sequence of the putative hmtPAP and its domain organization. Presented are cDNA and amino acid sequences available in the human genomic databases under accession nos: AK022188 and Q9HA74, respectively. Protein sequence is shown below corresponding DNA coding sequence using one-letter code. Asterisk indicates termination codon. Numbering refers to the amino acid sequence. The coding region is 1746 nt long and corresponds to 582 amino acid residues. The positions of protein domains detected by using bioinformatics tools (see text for details) are indicated on the right as follows: mTP, mitochondrial targeting peptide; RBD, SSF54928 RNA binding domain; NT, SSF81301 nucleotidyltransferase domain; PAP/25A core, PAP/25A core domain; PAP/25 associated, PAP/25A-associated domain. Note that NT and PAP/25A core domains partially overlap. The most probable cleavage site of mTP is marked with an arrow. Three discrepancies between genomic and cDNA sequence are specified on the right.