Table 4.
Category for primary disorders frequently described in the TOBYO database.
| Name of grouped category of disorders | Corresponding System Organ Class of MedDRA (version 19.1) | Gender: all, number of blogs and proportion among all disorders, n (%)a | Gender: male, number of blogs and proportion among each disorder, n (%)a | Gender: female, number of blogs and proportion among each disorder, n (%)a | Gender: unknown, number of blogs and proportion among each disorder, n (%)a | |
| Neoplasms benign, malignant, and unspecified | Neoplasms benign, malignant, and unspecified (including cysts and polyps) | 16,851 (31) | 4196 (25) | 12,621 (75) | 34 (0) | |
| Psychiatric and behavior disorders | Psychiatric disorders | 12,334 (23) | 4281 (35) | 7998 (65) | 55 (0) | |
| Kidney, urological, or genital disorders | Renal and urinary disorders | 4507 (8) | 774 (17) | 3710 (82) | 23 (1) | |
| Muscular, bone, or articular disorders | Musculoskeletal and connective tissue disorders | 4471 (8) | 648 (15) | 3813 (85) | 10 (0) | |
| Congenital disorders or abnormal chromosome | Congenital, familial, and genetic disorders | 2972 (6) | 1455 (49) | 1496 (50) | 21 (1) | |
| Neurological disorders | Nervous system disorders | 2877 (5) | 1171 (41) | 1691 (59) | 15 (1) | |
| Endocrine, nutritional, or metabolic disorders | Metabolism and nutrition disordersb | 2269 (4) | 636 (28) | 1626 (72) | 7 (0) | |
| Digestive system disorders | Gastrointestinal disorders | 1876 (4) | 773 (41) | 1093 (58) | 10 (1) | |
| Circulatory conditions | Cardiac disorders | 1523 (3) | 933 (61) | 580 (38) | 10 (1) | |
| Infections and infestations | Infections and infestations | 849 (2) | 480 (57) | 357 (42) | 12 (1) | |
| Blood, hematopoietic, or immunological disorders | Blood and lymphatic system disorders | 777 (1) | 314 (40) | 458 (59) | 5 (1) |
|
| Skin disorders | Skin and subcutaneous tissue disorders | 755 (1) | 230 (31) | 521 (69) | 4 (1) | |
| Others | 1949 (4) |
aNumber of blogs equals number of patients. Because of rounding, total values for proportion are not always 100%.
bThere was an another possible MedDRA coding: endocrine disorders.