Table 5.
Characteristics of severe congenital malaria
| Authors, year of publication | Sex | Birth weight (kg) | Previous residence of mother | Country of birth | Diagnostics | Parasitaemia | Body temperature (°C) | Hemoglobin level (g/dl) | Treatment | Outcome | Concomitant medication | Comment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Penazzato et al. [26], 2007 | – | 3.13 | Nigeria | Italy | MIC + PCR | 0.01% | – | 5.4 | Quinine sulphate 20 mg/kg/d for 5 days | Recovered without sequelae | Zidovudine | Mother HIV positive, no materno-foetal transmission of HIV |
| Jenkins et al. [27], 1957 | M | 4 | East Africa | England | MIC | – | 40 | 6.8 | Proguanil 0.25 g daily for 5 days followed by: chloroquine sulphate ¼ tablet twice daily for 2 days, then ¼ tablet daily for 2 days, then ¼ tablet weekly for 3 weeks | Recovered without sequelae | Penicillin, potassium permanganate baths, local aqueous gentian violet 0.66% | Pubic rash after day 3 |
| Erythromycin | Given on suspicion with proguanil | |||||||||||
| Ferrous sulphate |
MIC microscopy, PCR polymerase chain reaction, M male, – not mentioned in the original publication