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. 2017 Mar 11;14:26. doi: 10.1186/s12986-017-0174-6

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Impacts on bone mineral density and relationship with serum biomarkers. The effects of high fat and low fat diet containing varying levels of vitamin D on bone mineral density were analyzed using DEXA a No statistical differences observed between vitamin D groups. Differences between all lean and obese mice were significant for bone mineral density (^a p = 0.004; ^b p < 0.0001; ^c p < 0.008). Bone mineral density was not correlated with serum 25-OH b or 1,25-(OH)₂ vitamin D c, but was correlated with serum intact PTH (R² = 0.32, ****p < 0.0001) d