Fig. 4.
Density of allelic and non-allelic methylation versus gene expression correlation (R) and cumulative distribution of the absolute allelic and non-allelic correlation (|R|) for each dataset. a Density plot of significant (p < 0.05) correlations detected among sites (NCpG = 241,687, Ntests = 441,931) tested for allelic and non-allelic correlation for CpGs measured via MCC-Seq. b Density plot of significant correlations for sites (NCpG = 40,315, Ntests = 58,106) with methylation estimated by WGBS. c Empirical cumulative density function (ECDF) plot of the absolute correlation for sites evaluated using MCC-Seq. d ECDF for sites evaluated by WGBS. e Smoothed color density scatter plot of sites comparing significant non-allelic (x-axis) and allelic (y-axis) correlation (p < 0.05 for both correlation tests) for MCC-Seq. Red indicates high density, blue indicates low density, and white indicates no data. f Smoothed color density scatter plot of significant non-allelic versus allelic correlations for WGBS