Fig. 7.

a The distribution of the mean methylation of CpGs by ChromHMM state, for CpGs in ChromHMM states where we see high correlation between gene expression and H3K27ac (left) or H3K4me1 (right) histone peaks. Bar graphs show the log2 mean allelic ratio of the methylation on the high gene expression allele versus the low gene expression allele (green; indicating p < 0.05) b Positional distribution of CpGs by distance from the center of the ChromHMM state, for all the ChromHMM states having at least 100 CpGs c Summary of log2 mean allelic methylation ratio of CpGs at each distance from the center of the ChromHMM state bin, for the high gene expression allele versus low gene expression allele