. Author manuscript; available in PMC: 2018 Mar 1.

Published in final edited form as: Aliment Pharmacol Ther. 2017 Jan 24;45(6):844–854. doi: 10.1111/apt.13951

Table 2a.

Advanced MRI-derived measures by steatosis grade at baseline and week 24 – median (IQR)

MRI measure	Histology Determined Steatosis Grade
	Steatosis 1	Steatosis 2	Steatosis 3	P-Value
Baseline	N = 14	N = 13	N = 23
PDFF (%)	9.0 (3.3)	13.5 (6.8)	22.4 (10.0)	<.0001
TLV (mL)	1553.0 (363.9)	1646.5 (544.2)	2081.8 (615.2)	0.0003
TLFI (% mL)	124.8 (50.9)	206.8 (134.6)	520.3 (196.2)	<.0001
Week 24	N = 14	N = 13	N = 8
PDFF (%)	7.8 (4.4)	16.9 (9.0)	20.7 (2.7)	0.0011
TLV (mL)	1484.2 (494.7)	2012.9 (664.6)	1950.1 (650.5)	0.0745
TLFI (% mL)	116.6 (102.4)	412.0 (297.3)	430.6 (149.1)	0.0015

Abbreviations: MRI, magnetic resonance imaging; PDFF, proton-derived fat fraction; TLV, total liver volume; TLFI, total liver fat index.

Wilcoxon between steatosis grade 1 and grade 3, performed on all continuous/ordinal variables.