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. Author manuscript; available in PMC: 2017 Mar 11.
Published in final edited form as: FASEB J. 2015 Jul 6;29(10):4256–4267. doi: 10.1096/fj.14-259804

Figure 5. Rexinoid transactivation dose-response curves on a DR-5 element.

Figure 5

Dose-response curves were obtained by exposure to increasing concentrations of rexinoids in a gene reporter assay after co-transfection of Nur77, RXRγ and a reporter gene containing a DR-5 responsive element in HEK-293T cells. Data points represent means ± SEM expressed in percent of baseline Firefly/YFP ratios. These curves are representative of 3–5 independent experiments (pharmacological parameters can be found in Table 2).