Table 2.

ARF status in human cancers

Tissue type	ARF status	Frequency (%)	Ref
Breast	Low mRNA	77	70
	Promoter methylation	50
	HD	11.5
	LOH	27
	High mRNA	17
	No alteration	88
	Promoter methylation	24	71
Bladder	Promoter methylation	56	72
	LOH	22	68
	HD	14
	Mutation	2
Colon	Promoter methylation	33	73
	Promoter methylation	50.8	74
	Promoter methylation	28.2	80
	Promoter methylation	32	75
Liver	Promoter methylation	25	76
	HD	4
	LOH	16
	Promoter methylation	12	77
	HD	2.3	67
	Mutation	4.6
	High mRNA	93.2
Gastric	Promoter methylation (diffuse type)	45.5	78
	Promoter methylation (intestinal)	25
Lung	Promoter methylation	30	69
	LOH	26
	Promoter methylation	8	79
Oral	Promoter methylation	18	66
	HD	12
	Promoter methylation	43.8	64
	HD	26.5
Prostate	Promoter methylation	6.25	65
	HD	6.25
Kidney	HD	23.5	81
Brain	Promoter methylation	22	79

HD: Homologus Deletion, LOH: Loss Of Heterozygosity.