TABLE II.
Outcome | Controlled severe asthma (N = 15)
|
Achieved control with triamcinolone (N = 24)
|
Did not achieve control with triamcinolone (N = 17)
|
|||
---|---|---|---|---|---|---|
Baseline | After triamcinolone | Baseline | After triamcinolone | Baseline | After triamcinolone | |
AQLQ score* | 6.4 (5.9–6.6) | 6.6† (6.5–6.9) | 5.2 (4.1–5.9) | 6.3‡ (5.4–6.6) | 4.9 (3.9–5.5) | 5.0 (4.1–5.8) |
Blood eosinophils (%)§ | 7.9 (5.5–10.3) | 1.7* (1.0–3.3) | 5.4 (3.8–8.9) | 2.1‡ (1.0–2.2) | 5.8 (3.9–10.0) | 2.6* (1.2–3.3) |
Exhaled nitric oxide (ppb)§ | 28 (11–58) | 13‡ (8–19) | 25 (19–77) | 16‡ (11–25) | 36 (21–46) | 26‖ (15–42) |
FEV1 (% predicted) | 95 (84–105) | 99‖ (86–129) | 89 (71–97) | 92‖ (86–97) | 86 (74–103) | 79 (75–89) |
IQR, Interquartile range.
Data are from participants who completed the study. Values represent the median (IQR).
Maximum score on the AQLQ is 7, with higher scores representing greater asthma-related quality of life.
P < .01 vs baseline.
P < .001 vs baseline.
Data were logarithmically transformed before analysis.
P < .05 vs baseline.