Figure 4.

Cirrhosis in screening hemochromatosis. Percentages of participants in population-based studies [3, 172, 179, 180] and in an archived liver biopsy collection (second 2000 publication) [181] discovered to have HFE p.C282Y homozygosity who were previously diagnosed or were subsequently demonstrated to have advanced hepatic fibrosis or cirrhosis by biopsy [3, 170, 172, 180, 181]. Greater proportions of men than women had cirrhosis. See cirrhosis prevalence in nonscreening hemochromatosis cases in Figure 3.