Table 2.
Univariate regression analysis to determine predictors (p < 0.15) of allogeneic blood transfusion and each type of excessive postoperative blood loss in the study patients.
| Variables | BT | THL > 2.7 mg/dL | ETBL > 348.6 mL | DV/kg > 10.6 mL/kg | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Odds ratio | 95% CI | p value | Odds ratio | 95% CI | p value | Odds ratio | 95% CI | p value | Odds ratio | 95% CI | p value | |
| Age | 1.021 | 0.955 to 1.091 | 0.54 | 0.996 | 0.949 to 1.046 | 0.879 | 0.959 | 0.916 to 1.005 | 0.08♯ | 1.019 | 0.969 to 1.070 | 0.47 |
| Male gender | 1.050 | 0.289 to 3.819 | 0.94 | 1.207 | 0.466 to 3.123 | 0.699 | 5.009 | 2.269 to 11.060 | 0.0001♯ | 2.250 | 0.962 to 5.261 | 0.06♯ |
| Right side | 1.827 | 0.647 to 5.163 | 0.26 | 0.727 | 0.335 to 1.581 | 0.421 | 0.794 | 0.371 to 1.698 | 0.55 | 0.849 | 0.393 to 1.834 | 0.68 |
| Weight | 0.948 | 0.903 to 0.996 | 0.03 | 0.986 | 0.953 to 1.019 | 0.394 | 1.060 | 1.027 to 1.093 | 0.0003♯ | 0.946 | 0.911 to 0.983 | 0.004♯ |
| Height | 1.025 | 0.962 to 1.099 | 0.45 | 0.997 | 0.947 to 1.049 | 0.893 | 1.119 | 1.065 to 1.175 | <0.0001♯ | 1.010 | 0.961 to 1.061 | 0.70 |
| BMI | 0.809 | 0.701 to 0.934 | 0.004♯ | 0.964 | 0.879 to 1.057 | 0.437 | 1.052 | 0.969 to 1.143 | 0.22 | 0.811 | 0.725 to 0.907 | 0.0002♯ |
| Antiplatelet agent use | 1.082 | 0.235 to 4.975 | 0.92 | 0.532 | 0.121 to 2.341 | 0.404 | 0.238 | 0.031 to 1.807 | 0.17 | 0.858 | 0.246 to 2.998 | 0.81 |
| ASA physical status grade 3-4 | 1.245 | 0.440 to 3.519 | 0.68 | 0.771 | 0.358 to 1.661 | 0.507 | 0.615 | 0.288 to 1.311 | 0.21 | 0.771 | 0.358 to 1.661 | 0.51 |
| CCI | 1.141 | 0.694 to 1.875 | 0.60 | 0.931 | 0.634 to 1.367 | 0.714 | 0.811 | 0.552 to 1.191 | 0.29 | 0.895 | 0.609 to 1.317 | 0.57 |
| Comorbidities | ||||||||||||
| HT | 0.895 | 0.279 to 2.868 | 0.85 | 1.168 | 0.455 to 2.992 | 0.748 | 0.670 | 0.292 to 1.539 | 0.35 | 0.937 | 0.382 to 2.296 | 0.89 |
| RA | n/a | n/a | n/a | n/a | 0.99 | |||||||
| Femorotibial angle | 0.980 | 0.901 to 1.066 | 0.64 | 1.01 | 0.953 to 1.071 | 0.734 | 0.983 | 0.924 to 1.046 | 0.58 | 0.986 | 0.927 to 1.050 | 0.67 |
| OA KL grade 4 | 1.589 | 0.499 to 5.058 | 0.43 | 0.982 | 0.439 to 2.199 | 0.960 | 0.883 | 0.403 to 1.935 | 0.76 | 1.402 | 0.598 to 3.287 | 0.44 |
| Preoperative ROM | 1.028 | 0.998 to 1.060 | 0.07♯ | 1.007 | 0.987 to 1.028 | 0.490 | 1.024 | 1.002 to 1.046 | 0.03♯ | 1.021 | 0.999 to 1.044 | 0.06♯ |
| Preoperative laboratory values | ||||||||||||
| Hb | 0.257 | 0.144 to 0.459 | <0.0001♯ | 2.226 | 1.556 to 3.184 | <0.0001♯ | 1.894 | 1.355 to 2.647 | 0.0002♯ | 1.200 | 0.872 to 1.652 | 0.26 |
| Platelet count | 0.997 | 0.990 to 1.004 | 0.37 | 1.003 | 0.999 to 1.008 | 0.118♯ | 0.999 | 0.994 to 1.004 | 0.69 | 0.995 | 0.990 to 1.001 | 0.09♯ |
| aPTT | 0.963 | 0.779 to 1.190 | 0.73 | 0.967 | 0.823 to 1.135 | 0.678 | 1.044 | 0.895 to 1.217 | 0.59 | 0.974 | 0.830 to 1.144 | 0.75 |
| INR | 26313.398 | 14.063 to 49234185.914 | 0.008♯ | 0.182 | 0.000 to 156.350 | 0.621 | 0.476 | 0.001 to 335.973 | 0.82 | 0.231 | 0.000 to 193.500 | 0.67 |
| CrCl | 0.969 | 0.942 to 0.996 | 0.03♯ | 1.003 | 0.987 to 1.019 | 0.765 | 1.026 | 1.011 to 1.040 | 0.0006♯ | 0.981 | 0.963 to 1.001 | 0.06♯ |
| Albumin | 0.867 | 0.759 to 0.989 | 0.03♯ | 0.992 | 0.892 to 1.102 | 0.877 | 0.969 | 0.874 to 1.075 | 0.55 | 1.116 | 0.998 to 1.247 | 0.05♯ |
| General anesthesia | 1.191 | 0.147 to 9.631 | 0.87 | 1.355 | 0.292 to 6.279 | 0.698 | 1.301 | 0.281 to 6.021 | 0.74 | 1.355 | 0.292 to 6.279 | 0.70 |
| Operative time | 0.965 | 0.931 to 1.001 | 0.05♯ | 0.998 | 0.975 to 1.021 | 0.838 | 0.990 | 0.968 to 1.014 | 0.41 | 0.998 | 0.975 to 1.021 | 0.84 |
| Large prosthesis size | 0.831 | 0.260 to 2.653 | 0.76 | 1.368 | 0.608 to 3.078 | 0.448 | 4.522 | 2.071 to 9.875 | 0.0002♯ | 2.616 | 1.203 to 5.690 | 0.02♯ |
BT: blood transfusion; THL: total hemoglobin loss; ETBL: estimated total blood loss; RD/kg: drainage volume per kg; CI: confidence interval.
BMI: body mass index; ASA: American Society of Anesthesiologist; CCI: Charlson Comorbidity Index,
HT: hypertension; RA: Rheumatoid arthritis; OA: osteoarthritis; KL: Kellgren-Lawrence; ROM: range-of-motion,
Hb: hemoglobin; aPTT: activated partial thromboplastin time; INR: international normalized ratio; CrCl: creatinine clearance.
♯: significant value with p < 0.15.