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. Author manuscript; available in PMC: 2018 Mar 1.

Published in final edited form as: Mol Genet Metab. 2016 Dec 8;120(3):198–206. doi: 10.1016/j.ymgme.2016.12.002

Table 1.

Biochemical properties of mouse CPS1 in response to NCG and NAG.

Substrate or activator	K_m or K_a (mM)		V_max (μmol/min/mg)
Substrate or activator	NCG	NAG	NCG	NAG
ATP	6.3 ± 1.2	2.7 ± 0.6	1.4 ± 0.1	2.1 ± 0.2
Bicarbonate	5.2 ± 0.8	7.8 ± 0.6	0.56 ± 0.01	1.4 ± 0.1
Ammonium	0.88 ± 0.12	0.27 ± 0.35	0.64 ± 0.01	1.5 ± 0.1
NCG or NAG	2.23 ± 0.06	0.13 ± 0.05	0.92 ± 0.02	1.51 ± 0.05