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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Mol Genet Metab. 2017 Jan 10;120(3):229–234. doi: 10.1016/j.ymgme.2017.01.003

Fig. 4.

Fig. 4

Hepatic ChREBP signaling in 66–88 week-old rAAV-treated G6pc−/− mice. For hepatic G6P and quantitative RT-PCR, the data were analyzed for wild-type (+/+, n = 12) and AAV-NT (n = 22) mice after 24 hours of fasting. (A) Quantification of G6pt, Chrebp and Mlx mRNA by real-time RT-PCR. (B) Hepatic G6P contents. (C) Immunohistochemical analysis of hepatic ChREBP nuclear localization and quantification of nuclear ChREBP-translocated cells. Representative plates shown are at magnifications of x400, analyzed in wild-type (+/+, n = 5), AAV-NT, including AAV (n = 6), and AAV-low-NT (n = 6) mice. Data represent the mean ± SEM; **P < 0.005.