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. 2004 Dec 1;18(23):2941–2951. doi: 10.1101/gad.1239304

Figure 4.

Figure 4.

E2F6 binds to the same E2F-repressor site as E2F4. (A) Schematic of cdc6 luciferase reporter constructs assayed in the reporter chromatin immunoprecipitation assay. (B) Chromatin immunoprecipitation assay for interactions of E2F3, E2F4, and E2F6 with the cdc6 wild-type (WT) and mutant reporter constructs harboring mutations within the E2F sites at the -1 and -36 positions from the transcription start site (indicated by arrow). (Top panel) wild-type (WT) mouse embryo fibroblasts. (Bottom panel) E2F4-/- mouse embryo fibroblasts.