Figure 3.
(A) Dot plots depicting cytokine production in supernatant from peripheral blood mononuclear cells (PBMC) from both patients and healthy controls (n = 5) after stimulation of 106 PBMC with PMA-ionomycin (PMA+I) or heat-killed C. albicans (HKCA). Every symbol indicates an individual. US, unstimulated. (B) T lymphocyte cultures were stimulated for 24 h with IFN-γ, IL-27, or IL-6 and mRNA expression levels of CXCL9, CXCL10, and CD274 (PD-L1) were determined by real-time quantitative Taqman PCR. Data were normalized to the housekeeping gene, ABL. *P < 0.05, **P < 0.01, ***P < 0.001 when compared with healthy controls.