Table 2.
Abbreviations, full names, and TaqMan probes used to assess gene expression in the frontal cortex of MA and DLB cases in the present study.
| Gene | Full name | Reference |
|---|---|---|
| Housekeeping genes | ||
| GUS-B | β-glucuronidase | Hs00939627_m1 |
| XPNPEP1 | X-prolylaminopeptidase (aminopeptidase P) 1 | Hs00958026_m1 |
| AARS | Alanyl-tRNA synthetase | Hs00609836_m1 |
| HPRT | Hypoxanthine phosphoribosyltransferase 1 | Hs_02800695_m1 |
| Genes encoding proteins of mitochondria and energy metabolism-related molecules | ||
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8 kDa | Hs00159575_m1 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | Hs01561430_m1 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | Hs01071117_m1 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12 kDa | Hs00427185_m1 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18 kDa | Hs00188142_m1 |
| NDUFB10 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22 kDa | Hs00605903_m1 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20 kDa | Hs00257018_m1 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23 kDa | Hs00159597_m1 |
| SDHB | Succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | Hs00268117_m1 |
| UQCRB | Ubiquinol-cytochrome c reductase binding protein | Hs00559884_m1 |
| UQCR11 | Ubiquinol-cytochrome c reductase, complex III subunit XI | Hs00907747_m1 |
| COX7A2L | Cytochrome c oxidase subunit VIIa polypeptide 2 like | Hs00190880_m1 |
| COX7C | Cytochrome c oxidase subunit VIIc | Hs01595220_g1 |
| ATP5D | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | Hs00961521_m1 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 | Hs01096582_m1 |
| ATP5H | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d | Hs01046892_gH |
| ATP5L | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G | Hs00538946_g1 |
| ATP5O | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit | Hs00426889_m1 |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 | Hs00222625_m1 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | Hs00608066_m1 |
| ATP4A | ATPase, H+/K+ exchanging, alpha polypeptide | Hs00167575_m1 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | Hs00193110_m1 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | Hs01072388_m1 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | Hs00977530_m1 |
| FAM82A2 | Family with sequence similarity 82, member A2 | Hs00216746_m1 |
| LHPP | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase | Hs00383379_m1 |
| SLC6A6 | Solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | Hs00161778_m1 |
| SLC25A31 | Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 | Hs00229864_m1 |
| TOMM40 | Translocase of outer mitochondrial membrane 40 homolog (yeast) | Hs01587378_mH |
| ZNF642 | Zinc finger protein 642 | Hs01372953_m1 |
| Purine metabolism genes | ||
| ADA | Adenosine deaminase | Hs01110945_m1 |
| AK1 | Adenylate kinase (AK) 1 | Hs00176119_m1 |
| AK2 | AK 2 | Hs01123132_g1 |
| AK4 | AK 4 | Hs03405743_g1 |
| AK5 | AK 5 | Hs00952786_m1 |
| AK7 | AK 7 | Hs00330574_m1 |
| APRT | Adenine phosphoribosyltransferase | Hs00975725_m1 |
| DGUOK | Deoxyguanosine kinase | Hs00176514_m1 |
| ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1 | Hs00969559_m1 |
| ENTPD2 | Ectonucleoside triphosphate diphosphohydrolase 2 | Hs00154301_m1 |
| ENTPD3 | Ectonucleoside triphosphate diphosphohydrolase 3 | Hs00928977_m1 |
| NME1 | Non-metastatic cells 1, protein expressed in (nucleoside-diphosphate kinase) | Hs02621161_s1 |
| NME3 | Non-metastatic cells 3, protein expressed in (nucleoside-diphosphate kinase) | Hs01573874_g1 |
| NME4 | Non-metastatic cells 4, protein expressed in (nucleoside-diphosphate kinase) | Hs00359037_m1 |
| NME5 | Non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase) | Hs00177499_m1 |
| NME6 | Non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase) | Hs00195083_m1 |
| NME7 | Non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase) | Hs00273690_m1 |
| NT5C | 5′, 3′-nucleotidase, cytosolic | Hs00274359_m1 |
| NT5E | 5′-nucleotidase, ecto (CD73) | Hs00159686_m1 |
| PNP | Purine nucleoside phosphorylase | Hs01002926_m1 |
| POLR3B | Polymerase (RNA) III (DNA directed) polypeptide B | Hs00932002_m1 |
| PRUNE | Prune homolog (Drosophila) | Hs00535700_m1 |
| Nucleolar, rRNAs, and genes encoding ribosomal protein | ||
| NCL | Nucleolin | Hs01066668_m1 |
| NPM1 | Nucleophosmin (nucleolar phospho-protein B23, numatrin) | Hs02339479_m1 |
| NPM3 | Nucleophosmin/nucleoplasmin 3 | Hs00199625_m1 |
| rRNA 28S | RNA, 28S ribosomal 5 | Hs03654441_s1 |
| rRNA 18S | Eukaryotic 18S rRNA | Hs99999901_s1 |
| UBTF | Upstream binding transcription factor, RNA polymerase I | Hs01115792_g1 |
| RPL5 | Ribosomal protein L5 | Hs_03044958_g1 |
| RPL7 | Ribosomal protein L7 | Hs_02596927_g1 |
| RPL21 | Ribosomal protein L21 | Hs_00823333_s1 |
| RPL22 | Ribosomal protein L22 | Hs_01865331_s1 |
| RPL23A | Ribosomal protein L23A | Hs_01921329_g1 |
| RPL26 | Ribosomal protein L26 | Hs_00864008_m1 |
| RPL27 | Ribosomal protein L27 | Hs_03044961_g1 |
| RPL30 | Ribosomal protein L30 | Hs_00265497_m1 |
| RPL31 | Ribosomal protein L31 | Hs_0101549_g1 |
| RPS3A | Ribosomal protein S3A | Hs_00832893_sH |
| RPS5 | Ribosomal protein S5 | Hs_00734849_g1 |
| RPS6 | Ribosomal protein S6 | Hs_04195024_g1 |
| RPS10 | Ribosomal protein S10 | Hs_01652370_gH |
| RPS13 | Ribosomal protein S13 | Hs_01011487_g1 |
| RPS16 | Ribosomal protein S16 | Hs_01598516_g1 |
| RPS17 | Ribosomal protein S17 | Hs_00734303_g1 |
| Cytokines and mediators of the inflammatory responses | ||
| C1QL1 | Complement component 1, q subcomponent 1 | Hs00198578_m1 |
| C1QTNF7 | C1q and tumor necrosis factorY related protein 7 | Hs00230467_m1 |
| C3AR1 | Complement component 3a receptor 1 | Hs00377780_m1 |
| CLEC7A | C-type lectin domain family 7, member A | Hs01124746_m1 |
| CSF1R | Colony-stimulating factor 1 receptor | Hs00911250_m1 |
| CSF3R | Colony-stimulating factor 1 receptor | Hs00167918_m1 |
| CST7 | Cystatin F (leukocystatin) | Hs00175361_m1 |
| CTSC | Cathepsin C | Hs00175188_m1 |
| CTSS | Cathepsin S | Hs00356423_m1 |
| IL1B | Interleukin-1B | Hs01555410_m1 |
| IL6 | Interleukin-6 | Hs00985639_m1 |
| IL6ST | Interleukin-6 signal transducer | Hs00174360_m1 |
| IL8 | Interleukin-8 | Hs00174103_m1 |
| IL10 | Interleukin-10 | Hs00961622_m1 |
| IL10RA | Interleukin-10 receptor A | Hs00155485_m1 |
| IL10RB | Interleukin-10 receptor B | Hs00609836_m1 |
| TGFA1 | Transforming growth factor-A1 | Hs00998133_m1 |
| TGFA2 | Transforming growth factor-A2 | Hs00234244_m1 |
| TLR4 | Toll-like receptor 4 | Hs01060206_m1 |
| TLR7 | Toll-like receptor 7 | Hs00152971_m1 |
| TNF | Tumor necrosis factor | Hs01113624_m1 |
| TNFRSF1A | Tumor necrosis factor receptor superfamily member 1a | Hs01042313_m1 |
| Olfactory receptor (OR) and taste receptor (TASR) genes | ||
| OR2D2 | OR, family 2, subfamily D, member 2 | Hs00999189_s1 |
| OR2J3 | OR, family 2, subfamily J, member 3 | Hs01943871_g1 |
| OR2L13 | OR, family 2, subfamily L, member 13 | Hs00380097_m1 |
| OR2T1 | OR, family 2, subfamily T, member 1 | Hs01661970_s1 |
| OR2T33 | OR, family 2, subfamily T, member 33 | Hs04230793_gH |
| OR4F4 | OR, family 4, subfamily F, member 4 | Hs03406040_gH |
| OR6F1 | OR, family 6, subfamily F, member 1 | Hs01054972_s1 |
| OR10G8 | OR, family 10, subfamily G, member 8 | Hs01943074_g1 |
| OR11H1 | OR, family 11, subfamily H, member 1 | Hs03406084_gH |
| OR51E1 | OR, family 51, subfamily E, member 1 | Hs02339849_s1 |
| OR52H1 | OR, family 52, subfamily H, member 1 | Hs01661724_s1 |
| OR52L1 | OR, family 52, subfamily L, member 1 | Hs02339119_g1 |
| OR52M1 | OR, family 52, subfamily M, member 1 | Hs01098608_s1 |
| TAS2R4 | TASR, type 2, member 4 | Hs00249946_s1 |
| TAS2R5 | TASR, type 2, member 5 | Hs01549633_s1 |
| TAS2R10 | TASR, type 2, member 10 | Hs00256794_s1 |
| TAS2R13 | TASR, type 2, member 13 | Hs01059805_s1 |
| TAS2R14 | TASR, type 2, member 14 | Hs00256800_s1 |
| TAS2R50 | TASR, type 2, member 50 | Hs00604351_s1 |