Figure 1.

The dual regression proceeds in two stages. (A) In the first stage, subject-specific timecourses (blue circle) for each template network are extracted using a multivariate spatial regression of the template maps against each subjects FMRI data. (B) In the second stage, the subject-specific timecourses from stage 1 are used in a second multivariate regression against the subjects' FMRI data to identify the subject-specific spatial maps (red circle) corresponding to each template network of interest.