Figure 3.

Amount of flanking Alu sequence at different distances from edited and unedited Alus. All Alus for which ≥80% of the genomic extent of the Alu was sequenced were included in this analysis. For each Alu, the amount of flanking Alu sequence in the opposite orientation (A) or same orientation (B) in successive 1-kb windows was recorded. For each distance, the flanking Alu sequences in the 1-kb window 5′ and 3′ of the reference Alu were combined. The data presented are the average amount of Alu sequence flanking all edited Alus (gray bars) or unedited Alus (black bars).