Table 3.
Univariate and multivariate analyses of disease-free survival
| Factor | n | Number of recurrences/ deaths | p-value* | p-value** | HR (95% CI) |
|---|---|---|---|---|---|
| Age, years | |||||
| < 70/≥ 70 | 58/28 | 23/11 | 0.941 | ||
| Gender | |||||
| Male/Female | 73/13 | 32/2 | 0.091 | ||
| Tumor site | |||||
| OPC/HPC | 51/35 | 18/16 | 0.377 | ||
| PS | |||||
| ≤ 1/≥ 2 | 72/14 | 25/9 | 0.079 | ||
| Histology | |||||
| SCC/Other | 83/3 | 34/0 | 0.204 | ||
| Chemo | |||||
| +/– | 69/17 | 25/9 | 0.129 | ||
| T-stage | |||||
| T1–2/T3–4 | 57/29 | 16/18 | 0.001 | ||
| N-stage | |||||
| N0/N1–3 | 21/65 | 4/30 | 0.039 | 0.731 | 0.774 (0.180–3.333)/1 |
| c stage | |||||
| I–II/III–IVa-b | 17/69 | 2/32 | 0.017 | 0.297 | 0.340 (0.045–2.588)/1 |
| pSUVmax | |||||
| ≤ 9.0/> 9.0 | 49/37 | 14/20 | 0.009 | 0.055 | 0.499 (0.245–1.014)/1 |
* Univariate analyses using the log-rank test
**Multivariate analyses using the Cox regression model
Abbreviations: n, number of patients; HR, hazard rate; CI, confidence interval; OPC, oropharyngeal cancer; HPC, hypopharyngeal cancer; PS, Performance status; SCC, squamous cell carcinoma; chemo, chemotherapy; c stage, clinical stage; pSUVmax, the maximum standardized uptake value of the primary site.