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. 2016 Oct 8;7(48):78591–78604. doi: 10.18632/oncotarget.12519

Figure 6. Cell proliferation analysis.

Figure 6

To evaluate the impact of FTH1 expression and/or iron accumulation on cells, the proliferation of SK-N-SH-FTH1 and SK-N-SH-WT cells incubated in a 96-well plate was examined using a CCK-8 assay. In the absence of FAC, FTH1 overexpression did not interfere with SK-N-SH cell proliferation in vitro. However, a relatively high dose (500 μM) of FAC inhibited the growth of SK-N-SH-WT and SK-N-SH- FTH1 cells. Interestingly, the cells expressing FTH1 were more sensitive to FAC.