Table 2. Associations between tertiles of dietary iron intake and breast cancer risk from multivariable cox proportional hazards models, SU.VI.MAX cohort, france, 1994–2007a, b.
| N for cases/non-cases | HR (95% CI) | P-trend | |
|---|---|---|---|
| All women | 0.04 | ||
| Tertile 1 | 53/1495 | 1.00 | |
| Tertile 2 | 57/1492 | 1.18 (0.78, 1.79) | |
| Tertile 3 | 78/1471 | 1.67 (1.02, 2.71) | |
| Premenopausal women | 0.4 | ||
| Tertile 1 | 17/1045 | 1.00 | |
| Tertile 2 | 19/1094 | 1.05 (0.51, 2.18) | |
| Tertile 3 | 23/1051 | 1.39 (0.58, 3.29) | |
| Postmenopausal women | 0.04 | ||
| Tertile 1 | 36/1143 | 1.00 | |
| Tertile 2 | 38/1093 | 1.25 (0.75, 2.08) | |
| Tertile 3 | 55/1107 | 1.85 (1.02, 3.34) |
CI, confidence interval, HR, Hazard ratio, SU.VI.MAX, Supplémentation en Vitamines et Minéraux Antioxydants
a
Multivariable models were adjusted for age (timescale), energy intake without alcohol, intervention group of the initial SU.VI.MAX trial, number of 24-h dietary records, smoking status, educational level, physical activity, height, BMI, alcohol intake, family history of breast cancer, lipid intake, use of hormone replacement therapy, number of children and for premenopausal women: use of contraceptive pill, heavy period, and use of a hormonal intrauterine system.
b
Cut-offs for tertiles of dietary iron intake were 9.3 and 11.9 mg/d.