Table 1. Relationship between the expression level of ING4 and clinicopathological features of CRC patients.
| Variables | ING4 expression (n=509 cases) | ||
|---|---|---|---|
| Low (%) | High (%) | Pa | |
| All patients | 359 (100) | 150 (100) | |
| Age(years) | 1.000 | ||
| ≤ 65 | 147 (41) | 62 (41) | |
| >65 | 212 (59) | 88 (59) | |
| Gender | 0.280 | ||
| Males | 211 (59) | 80 (53) | |
| Females | 148 (41) | 70 (47) | |
| Depth of invasion* | 0.072 | ||
| T1/T2 | 14 (4) | 12 (8) | |
| T3/T4 | 340 (96) | 132 (92) | |
| Lymph node metastasis | <0.001 | ||
| N0 | 207(58) | 115 (77) | |
| N1/N2/N3 | 152 (42) | 35 (23) | |
| Distant metastasis# | 0.074 | ||
| M0 | 340(95) | 148 (99) | |
| M1 | 17 (5) | 2 (1) | |
| TNM stage | <0.001 | ||
| I | 41 (11) | 28 (19) | |
| II | 150 (42) | 92 (61) | |
| III | 150 (42) | 27 (18) | |
| IV | 18 (5) | 3 (2) | |
| Tumor diameter | 0.592 | ||
| ≤5 cm | 258 (72) | 104 (69) | |
| >5cm | 101 (28) | 46 (31) | |
| Differentiation$ | 0.692 | ||
| Poor | 57 (16) | 26 (18) | |
| Moderate/high | 299 (84) | 120 (82) | |
a
Two-sided Fisher's exact tests.
*
The depth of invasion of cancer in 11 patients cannot be assessed.
#
The distant metastasis of cancer in 2 patients cannot be assessed.
$
We lost the data of 7 CRC patients.